Crestor Side Effects – Common and Rare

Crestor Side Effects

Crestor is a synthetic statin medication, and it is one of the most popularly prescribed medicines for use in lowering cholesterol. Statin drugs like Crestor work by limiting the production of substance in the liver. Up to three quarters of the cholesterol found in the blood comes from the liver, thusly medications that slow this production process have shown to be effective at lowering the risk of cardiovascular disease over time. Statin drugs like Crestor work by stalling an enzyme known as HMG-CoA reductase, which contributes to the cholesterol manufacturing process, according to Wikipedia. However, while the heart health benefits of statins have been well documented, Crestor side effects can persist that can make using the medication difficult for some.

Crestor works to lower the amount of bad cholesterol and triglycerides in the blood stream. Bad cholesterol (LDL or low density lipoprotein) can affix itself to existing plaques in the arteries causing blockages. This can lead to sudden heart attacks. In persons who are high risk, such as those who have a family history, are overweight or obese, smoke or have limited amounts of physical activity, high levels of bad cholesterol can contribute to a much higher risk of heart disease.

Crestor’s effectiveness has been well proven, and users have benefitted from lowered cholesterol numbers and a long term reduction in cardiovascular illness risk. However, Crestor side effects can be challenging. Some of the adverse reactions encountered by users are mild and dissipate quickly with continued use. Other effects can be serious, and these are much rarer.

Mild Crestor side effects include those of the gastrointestinal tract. points out that these can include nausea and upset stomach as well as occasionally vomiting and diarrhea. While they are some of the most commonly reported side effects associated with the drug, in trials they have still occurred in a small percentage of users. In addition to these tummy troubles, other benign side effects include headaches and pain in the abdomen. Skin issues have also occurred as Crestor side effects, and RxList mentions some of the most common of these dermatological issues, like skin rashes, urticaria, hypersensitivity and an itching sensation.

Like other statin high cholesterol medications, one of the most serious rare side effects associated with Crestor has to do with the muscles. Although uncommon, Crestor side effects may include a condition that is known as rhabdomyolysis. This uncommon but serious condition can lead to failure of the kidneys. In rhabdomyolysis, enzymes and electrolytes are released from broken down skeletal muscles. According to, one compound in particular, called myoglobin, is especially poisonous to the kidney, which can lead to eventual failure of the organs. Rhabdomyolysis is not a common side effect of medications; however, it does occur rarely amongst Crestor side effects, as with other statin medications.

Aside from muscle problems, other serious risks associated with Crestor include liver problems and mental impairment. Liver problems may or may not be serious. Some people may simply experience unusual fluctuations in the enzymes produced by the liver, while a very small percentage of others may experience serious liver problems. In terms of neurological issues, some users may experience confusion and memory loss both as Crestor side effects. In mild cases, these periods of forgetfulness or disorientation may be minimal and infrequent. However, over time, some users have had serious mental effects from the medication.

Having high cholesterol can have serious and long term health implications. Diet and exercise are important in order to proactively maintain good health of the body and reduce the risk of serious health problems down the line. In some cases however, high cholesterol cannot be controlled with diet, exercise, supplements to lower cholesterol and lifestyle changes alone. In these instances, cholesterol medications are often used. There are many side effects attributed to statin drugs like Crestor, and a certain percentage of users discontinue the drugs after a period of time as the side effects persist. However there are also some benefits to the medicines as well, such as a reduced risk of cardiovascular problems in the long term. It is important that anyone taking or considering taking Crestor discuss it with their health care provider. He or she will be able to fully explain Crestor side effects and benefits to determine whether or not both the risk and benefit are right for you.